Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2006-05-09
2006-05-09
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C514S254090, C514S323000, C514S388000, C544S098000, C544S373000, C546S201000, C546S277400, C548S304700, C548S209000, C548S950000, C549S505000
Reexamination Certificate
active
07041668
ABSTRACT:
The present invention discloses and claims benzimidazole compounds of formula (I):in which A is aryl or heteroaryl; R1is selected from optionally substituted alkyl, alkoxy, aryl or heteroaryl, NH-lower alkyl or NH-cycloalkyl, or halogen, NH2; 1-imidazolyl or SO2Me; R2is selected from optionally substituted —CO-alkyl, —CO-cycloalkyl, —CO-aralkyl, —CO-aryl, —CO-alkoxy, aryl or aralkyl, or —CO-amino, CO—NHR3or CO—R3R4wherein R3and R4are selecteded independently from hydrogen, alkyl, hydroxyalkyl, alkoxyalkyl, fluoroalkyl, alkynyl, heteroalkyl, alkylheteroalkyl, aryl, aralkyl or together form an alkylene chain optionally containing one to 4 heteroatoms; a pharmaceutically acceptable salt or a prodrug thereof; the use of compounds of formula (I) for the treatment of cancer, and pharmaceutical compositions comprising a compound of formula (I) and one or more pharmaceutically acceptable adjuvants or diluents.
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Angouillant-Boniface Odile
Carrez Chantal
Clerc Francois
Depaty Isabelle
Deprets Stéphanie
Aventis Pharma S.A.
Balaram Gupta
Lee Susannah E.
Saeed Kamal A.
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