Substituted benzimidazole compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C548S304700, C548S307400, C548S248000, C546S273400, C544S121000, C544S132000, C544S370000, C514S378000, C514S338000, C514S234500, C514S254060

Reexamination Certificate

active

07138420

ABSTRACT:
Disclosed are substituted benzimidazole compounds of formula (I):wherein R1, R2, R3, R4and Xaare defined herein. The compounds of the invention inhibit Itk kinase and are therefore useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.

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