Substituted benzenesulfonyl-thioureas and pharmaceutical prepara

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514365, 514593, 546332, 548204, 548561, 549 77, 549498, 564 23, 564 40, A61K 3118, C07C31158

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active

056079761

ABSTRACT:
Substituted benzenesulfonylureas and -thioureas, processes for their preparation, their use for the production of pharmaceutical preparations, and pharmaceutical preparations containing them.
Substituted benzenesulfonylureas and -thioureas of the formula I ##STR1## exhibit effects on the cardiovascular system.

REFERENCES:
patent: 3494936 (1970-02-01), Weyer et al.
patent: 3917690 (1975-11-01), Weber et al.
patent: 3998968 (1976-12-01), Hitzel et al.
patent: 5215985 (1993-06-01), Murphy et al.
W. Linz et al., Cardiovascular Effects of the Novel Potassium Channel Opener (3S, 4R)-3-Hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-6-phenylsulfonylchroma ne Hemihydrate, Arzneimittel-Forschung/Drug Research, 42 (II), 10, 1180-1185 (1992).

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