Substituted benzazepines, their preparation and pharmaceutical c

Details Substituted benzazepines, their preparation and pharmaceutical c Substituted benzazepines, their preparation and pharmaceutical c

1989-03-13

1991-05-14

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

540594, 540595, A61K 3155, A61K 31495, C07D40302, C07D22316

Patent

active

050156390

ABSTRACT:
Disclosed herein are novel 1-substituted-2,3,4,5-tetrahydro-1H-3-benzazepines of the general formula I: ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are specified substituents.

REFERENCES:
patent: 3393192 (1968-07-01), Walter et al.
patent: 3609138 (1971-09-01), Mull et al.
patent: 4011319 (1977-03-01), Kaiser et al.
patent: 4187314 (1980-02-01), Holden et al.
patent: 4197297 (1980-04-01), Weinstock
patent: 4265889 (1981-05-01), Brush et al.
patent: 4284555 (1981-08-01), Gold et al.
patent: 4477378 (1984-10-01), Gold et al.
J. Richard Heys--High-Performance Liquid Chromatographic Studies of pH Dependence in the Isotopic Fractionation of Deuterated Benzazepines, J. Chromatography, 407, pp. 37-47 (1987).

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