Substituted benzamides and radioligand analogs and methods of us

Details Substituted benzamides and radioligand analogs and methods of us Substituted benzamides and radioligand analogs and methods of us

1994-12-09

1998-03-03

Kight, John

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

In an organic compound

546133, A61K 5100, A61M 3614

Patent

active

057231036

ABSTRACT:
This invention provides compounds of the formula I ##STR1## atom,! fluorine, chlorine, bromine, iodine, alkyl, alkenyl, alkynyl, alkoxy, alkenoxy, or alkynoxy, wherein R.sup.2 and R.sup.3 can also independently be H, wherein at least one of R.sup.1, R.sup.2, and R.sup.3 or lower alkyl. The invention also provides precursors of formula I, radioactive analogs of formula I, and methods of using the compounds for the identification of 5-HT-3 receptors and the detection and treatment of abnormal conditions associated therewith.

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