Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-11-22
2005-11-22
Powers, Fiona T. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S374000, C548S194000, C548S236000
Reexamination Certificate
active
06967212
ABSTRACT:
Compounds are provided which have the structurewherein Q is C or N; R2a, R2b, R2c, X1to X7, R1, R2, R3, R3a, R4, A, Y, m, and n are as defined herein, which compounds are useful as antidiabetic, hypolipidemic, and antiobesity agents. The present invention further provides a method for treating obesity and dyslipidemia in mammals including humans through simultaneous inhibition of peroxisome proliferator activated receptor-γ (PPARγ) and stimulation of peroxisome proliferator activated receptor-α (PPARα).
REFERENCES:
patent: 6506781 (2003-01-01), Cobb et al.
patent: 6653314 (2003-11-01), Cheng et al.
Cheng Peter T.
Zhang Hao
Bristol--Myers Squibb Company
Burton & Rodney
Powers Fiona T.
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