Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1993-12-16
1997-01-07
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540360, C07D20508, C07D40512, A61K 31395, A61K 31535
Patent
active
055917372
ABSTRACT:
New substituted azetidinones of the general Formula (I) which have been found to be potent elastase inhibitors and thereby useful anti-inflammatory and antidegenerative agents are described. ##STR1## wherein R.sub.4 is (a) ##STR2## or (b) ##STR3## where R.sub.x is carboxy C.sub.1-6 alkyl, benzyloxycarbonylC.sub.1-3 alkyl, or t-butoxycarbonylC.sub.1-3 alkyl,
wherein
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Doherty James B.
Dorn Conrad P.
Durette Philippe L.
Finke Paul E.
Hagmann William K.
Berch Mark L.
Merck & Co. , Inc.
Panzer Curtis C.
Rose David L.
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