Substituted aryloxy-3,3,3-trifluoro-2-propionic acids, esters an

Details Substituted aryloxy-3,3,3-trifluoro-2-propionic acids, esters an Substituted aryloxy-3,3,3-trifluoro-2-propionic acids, esters an

1975-11-10

1977-10-25

Morgenstern, Norman

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260295CA, 260448AD, 260463, 2605011, 260520C, 260559B, 260559D, 424300, 424301, 424308, 424309, 424316, 424317, 424324, 260521H, 560 56, 560 60, 560 62, 560 59, 560 63, C07C 6514, C07C 6502, C07C 6976

Patent

active

040555950

ABSTRACT:
Derivatives of 2-hydroxy-3,3,3-trifluoro-2-(alkyl or trifluoromethyl)propionic acid bearing a phenyl or naphthyl group linked to the 2-hydroxy group either directly or via an intermediate methylene group. The compounds reduce the concentrations of cholesterol, total esterified fatty acids or fibrinogen in the blood plasma of test animals and some compounds show anti-arthritic properties.

REFERENCES:
patent: 3347910 (1967-10-01), Bolhofer et al.
patent: 3363003 (1968-01-01), Bolhofer
patent: 3549690 (1970-12-01), Leigh et al.
patent: 3642869 (1972-02-01), Narayanan et al.
patent: 3721703 (1973-03-01), Nahm et al.
patent: 3740437 (1973-06-01), Harrison et al.
patent: 3954442 (1976-05-01), Becker et al.

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