Substituted (arylalkylaminobenzyl) aminopropionamide derivatives

Details Substituted (arylalkylaminobenzyl) aminopropionamide derivatives Substituted (arylalkylaminobenzyl) aminopropionamide derivatives

1994-03-22

1995-09-12

Kumar, Shailendra

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

514617, 514618, 514619, 564162, 564163, 564164, 564165, 564167, 564168, 564171, A61K 31165, C07C23305

Patent

active

054496926

ABSTRACT:
The invention provides new compounds of formula (I) ##STR1## wherein n is an integer of 1 to 4; each of R and R.sub.1, which may be the same or different, is hydrogen, halogen, trifluoromethyl or C.sub.1 -C.sub.4 alkoxy; R2 is hydrogen or C.sub.1 -C.sub.4 alkyl; and a pharmaceutically acceptable salts thereof; and wherein when, at the same time, R is hydrogen, R.sub.1 is hydrogen or halogen and n is one, then R.sub.2 is other than hydrogen or methyl; and of formula (IA) ##STR2## wherein R.sub.3 is halogen, and a pharmaceutical acceptable salt thereof, which are active on the central nervous system (CNS) and can be used in therapy as anti-epileptics, anti-Parkinson, neuroprotective, antidepressant, anti-spastic and hypnotic agents.

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