Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-11-21
1976-11-30
Killos, Paul J.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260390, 260395, 260463, 260468D, 260471R, 260473R, 260514D, 260520B, C07C 6976
Patent
active
039949567
ABSTRACT:
Substituted phenyl and naphthyl esters of PGE.sub.2 analogs, including the 16-alkyl, 16-fluoro, 16-phenoxy, and phenyl-substituted analogs, and their 15-epimers, and their racemic forms, and processes for producing them are disclosed. The products are useful for the same pharmacological and medical purposes as these PGE.sub.2 analogs, and are also useful as a means for obtaining highly purified 16,16-dimethyl-PGE.sub.2, 16-phenoxy-17,18,19,20-tetranor-PGE.sub.2, and 17-phenyl-18,19,20-trinor-PGE.sub.2.
REFERENCES:
patent: 3894062 (1975-07-01), Morozowich
Killos Paul J.
Nielsen Morris L.
Stein Bruce
The Upjohn Company
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