Substituted aminoquinolines as modulators of chemokine receptor

Details Substituted aminoquinolines as modulators of chemokine receptor Substituted aminoquinolines as modulators of chemokine receptor

1997-12-18

1999-07-06

Mach, D. Margaret M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ortho-hydroxybenzoic acid or derivative doai

514160, 514161, 514162, 514163, 514167, A61K 3147, A61K 31475, A61K 3149

Patent

active

059197765

ABSTRACT:
The present invention is directed to aminoquinolines of Formula I: ##STR1## (wherein R.sup.1, R.sup.2, R.sup.3, and R.sup.4 are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.

REFERENCES:
patent: 5441963 (1995-08-01), McDonald
patent: 5506235 (1996-04-01), Moyer
Chemical Abstracts 116:51112, Lanza, 1992.
Medline 96210126, Legler, 1996.
Medline 94089760, Eaves, 1993.
Medline 94044787, Hori, 1993.
Chemical Abstracts 124:143381, Bennett, 1995.
Chemical Abstracts 124:199641, Toggas, 1996.

Affiliated with

Also associated with

Rating

Substituted aminoquinolines as modulators of chemokine receptor does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted aminoquinolines as modulators of chemokine receptor , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted aminoquinolines as modulators of chemokine receptor will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-899134