Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-11-07
1982-04-06
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544322, 544320, 544324, 544316, 544310, C07D23920
Patent
active
043235700
ABSTRACT:
The present invention is directed to certain aminopyrimidines of the general formula ##STR1## wherein R.sup.1, R.sup.2, and R.sup.3 are hydrogen, halogen, alkoxy, alkylthio, or alkyl having 1 to 4 carbon atoms, or cycloalkyl having 3 to 5 carbon atoms and R.sup.4 is hydrogen or an aliphatic or aromatic acyl group, as well as physiologically compatible acid addition salts thereof. Compounds of the present invention are useful as blood pressure lowering agents and in the treatment of glaucoma.
REFERENCES:
patent: 3818033 (1974-06-01), Heyes et al.
patent: 3872121 (1975-03-01), Kummer et al.
patent: 3920655 (1975-11-01), Rufer et al.
patent: 4029792 (1977-06-01), Danielewicz
patent: 4108982 (1978-08-01), Amschler
Hackh's Chemical Dictionary, p. 16, fourth edition (1969), McGraw-Hill, NY.
Weygand-Hilgetag, Organisch Chemische Experimentierkunst, 4th Edition, Joh. Ambr. Barth, Leipzig (1970), 515-516.
B. Helwig, Modrine Arzneimittel, 4th edition (1972), 926-928.
Armah Ben
Cohnen Erich
Fleck Wolfgang
Stenzel Wolfgang
Beiersdorf Aktiengesellschaft
Rizzo Nicholas S.
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