Substituted aminobenzoates, their preparation and use

Details Substituted aminobenzoates, their preparation and use Substituted aminobenzoates, their preparation and use

1983-07-11

1985-05-07

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

560 46, C07C10172

Patent

active

045159807

ABSTRACT:
Novel lower-alkyl 2-(hydroxyphenylamino)benzoates, useful as inhibitors of lipoxygenase, are of the formula ##STR1## wherein R is hydrogen, lower-alkyl or lower-alkoxy; R' is hydrogen or lower-alkyl; R" is hydrogen, lower-alkyl or halo; and Alk is lower-alkyl. The compounds are prepared by de-etherification of the corresponding alkyl or benzyl ethers.

REFERENCES:
patent: 3819637 (1974-06-01), Bell
Molnar et al., Helv. Chim. Acta, 52, 401-408, (1969).
Legrand et al., Bull. Soc. Chim., France, 1969, 1173-82.
Chemical Abstracts, vol. 95, 1981, p. 782, abstract No. 80890q, Kim, D. H., "Synthesis of 5H-benzoxazolo[3,2-a]quinazolin-5-ones".

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