Substituted amides having antiinflammatory activity

Details Substituted amides having antiinflammatory activity Substituted amides having antiinflammatory activity

1978-12-22

1980-04-22

Helfin, Bernard

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260558R, 260558A, 260558D, 260558P, 260559R, 26050117, C07C 9116

Patent

active

041995287

ABSTRACT:
Compounds having the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein R.sub.1 is alkyl, cycloalkyl or aryl; R.sub.2 is acyl or sulfonyl; R.sub.3 is alkylamino, dialkylamino or a nitrogen containing heterocyclic group; R.sub.4 is alkoxy; A.sub.1 is a saturated bond or an alkylene group having 1 to 4 carbon atoms; and A.sub.2 is an alkylene group having 2 to 5 carbon atoms; have antiinflammatory activity.

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Millonig et al., Chemical Abstracts, 81, 163333(x), 1974.
Nakamura et al., Chemical Abstracts, 82, 14677(f), 1975.
Geller et al., Chemical Abstracts, 83, 141972(u), 1975.

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