Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1988-10-14
1992-12-29
Evans, Joseph E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 89, 514119, 546 22, 558190, 560 16, 560 38, 560 40, 562 10, 562 11, 562 15, C07F 938, C07F 940, A61K 3113, A61K 31185
Patent
active
051751534
ABSTRACT:
The present invention is novel substituted .alpha.-amino acids, pharmaceutical compositions, method of use, and preparations therefore having utility for treating disorders which benefit from blockade of aspartate and glutamate receptors.
REFERENCES:
patent: 4657899 (1987-04-01), Rzeszotarski et al.
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patent: 4918064 (1990-04-01), Cordi et al.
EPO Search Report (EP88 11 99 11) with references.
Neurology and Neurobiology vol. 24, "Excitatory Amino Acid Transmission", 1987 pp. 19-26.
"The Synthesis of p-Substituted D,L-Phenylglycines by the Amidoalkylation of Benzylchloride and N-Benzylbenzamide".
D. Ben-Ishai et al. Tetrahedran, vol. 33, pp. 2715-2717 (1977) SCRIP #1067, Jan. 13, 1986, p. 22.
Bigge Christopher F.
Drummond James T.
Gregor Vlad E.
Johnson Graham
Pavia Michael R.
Daignault Ronald A.
Evans Joseph E.
Warner-Lambert & Company
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