Substituted alpha-(2-tricyclo(3.3.1.13,7)-decylidene)benzeneacet

Details Substituted alpha-(2-tricyclo(3.3.1.13,7)-decylidene)benzeneacet Substituted alpha-(2-tricyclo(3.3.1.13,7)-decylidene)benzeneacet

1986-05-27

1988-05-17

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564180, C07C10326, C07C10322, A61K 31165

Patent

active

047452200

ABSTRACT:
Substituted .alpha.-[2'-tricyclo[3.3.1.1.sup.3,7 ]decylidene]-benzenacetamide derivatives of the formula: ##STR1## where the R.sup.1, R.sup.2 and R.sup.3 substitutents are independently selected from hydrogen, lower alkyl, lower alkoxy, halogen and trifluoromethyl, provided that at least one of such substitutents is hydrogen, have antihypoxia, antiparkinson, and/or anticonvulsant activities.

REFERENCES:
patent: 3624126 (1971-11-01), Narayanan
Fuks et al., Chem. Ber., 103, 564-572 (1970).
Chemical Abstracts 64: 19630h (1966).
Chemical Abstracts 65: 10524d (1966).
Aigami et al., "Biologically Active Polycycloalkanes, 1 Antiviral Adamantane Derivatives", J. Med. Chem. 18, 713-721 (1975).

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