Substituted alkylaminopyridazinone derivatives, process for...

Details Substituted alkylaminopyridazinone derivatives, process for... Substituted alkylaminopyridazinone derivatives, process for...

2005-08-16

2005-08-16

Dentz, Bernard (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S238000

Reexamination Certificate

active

06930110

ABSTRACT:
The invention relates to substituted alkylaminopyridazinone derivatives of the general Formula (I), (wherein R1is hydrogen or alkyl having 1-4 carbon atoms; one of X and Y stands for hydrogen or halogen and the other represents a group of the general Formula (II), R2is hydrogen or alkyl having 1-4 carbon atoms; n is 1, 2 or 3; R3stands for hydrogen, alkyl having 1-4 carbon atoms or aryl-(C1-4alkyl); Z stands for oxygen; or R3and Z together with the groups placed between them form a piperazine ring; and R4stands for hydrogen, halogen, trifluoromethyl or alkoxy having 1-4 carbon atoms) and pharmaceutically acceptable acid addition salts thereof. The invention compounds are useful in the treatment of anxiolytic conditions and cognitive disorders.

REFERENCES:
patent: 3931176 (1976-01-01), Houlihan
patent: 0 372 305 (1990-06-01), None
patent: 164 079 (1994-06-01), None
patent: WO 96 38441 (1996-12-01), None
patent: WO 99 64402 (1996-12-01), None

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