Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-09-12
2006-09-12
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S318000, C546S200000, C546S233000, C546S234000
Reexamination Certificate
active
07105544
ABSTRACT:
This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of reducing the body mass of a subject which comprises administering to the subject an amount of a compound of the invention effective to reduce the body mass of the subject. This invention further provides a method of treating a subject suffering from depression and/or anxiety which comprises administering to the subject an amount of a compound of the invention effective to treat the subject's depression and/or anxiety.
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S. Takekawa, et al., “T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist”, Eur. J. Pharmacol. 438(3), (2002) pp. 129-135.
U.S. Appl. No. 10/719,358, Marzabadi et al., filed Nov. 21, 2003, not yet published.
Chen Chien-An
Jiang Yu
Lu Kai
Marzabadi Mohammad R.
Wetzel John M.
Chang Celia
Darby & Darby
Synaptic Pharmaceutical Corporation
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