Substituted adamantyl dioxetanes

Details Substituted adamantyl dioxetanes Substituted adamantyl dioxetanes

1990-08-30

1993-06-15

Cintins, Marianne M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

549221, 549510, 549332, 536 41, 536 181, 536120, 536 2626, 536 267, 536 273, C07H 1524, C07F 906, C07D30500

Patent

active

052200051

ABSTRACT:
Dioxetane compounds reactable with an enzyme to release optically detectable eneregy are disclosed. These compounds have the formula: ##STR1## wherein T is a carboxylic acid or methoxy substituted adamantyl group bound to the ring through a spiro bond, Y is phenoxy or napthyloxy and X is methoxy, ethoxy or propoxy. Z is an enzyme cleavable group such that when cleaved by an enzyme, an electron rich moiety is left bound to the dioxetane ring.

REFERENCES:
patent: 4978614 (1990-12-01), Bronstein

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