Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic

Details Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic

1981-02-17

1982-09-21

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

424258, 424262, 424263, 546147, 546170, 546273, 26032613D, 26032613H, 26032612R, A61K 31405, C07D20934

Patent

active

043507042

ABSTRACT:
Substituted acyl derivatives of octahydro-1H-indole-2-carboxylic acid and the pharmaceutically acceptable salts thereof are produced by acylating a suitably substituted octahydro-1H-indole with a suitably activated substituted carboxylic acid and when desired hydrolyzing the resulting product. The compounds of the invention, their salts and pharmaceutical compositions thereof are useful as antihypertensive agents.

REFERENCES:
patent: 3929830 (1975-12-01), Richter et al.
patent: 4105776 (1978-08-01), Ondetti et al.
patent: 4116962 (1978-09-01), Ondetti et al.
patent: 4129566 (1978-12-01), Ondetti et al.
patent: 4154840 (1979-05-01), Ondetti et al.
patent: 4154935 (1979-05-01), Ondetti et al.
patent: 4199512 (1980-04-01), Ondetti et al.
patent: 4206121 (1981-06-01), Ondetti et al.

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