Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-07-19
2005-07-19
Seaman, D. Margaret (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S311000, C546S173000
Reexamination Certificate
active
06919353
ABSTRACT:
8-arylquinolines of formula (I) wherein the aryl group at the 8-position contains a meta two atom bridge to an optionally substituted phenyl or pyridyl group, are PDE4 inhibitors useful to treat asthma, chronic bronchitis, chronic obstructive pulmonary disease, arthritis, respiratory distress syndrome, allergic rhinitis, neurogenic inflammation, pain, rheumatoid arthritis, and other diseases. R1-R7and Ar are as in claim1.
REFERENCES:
patent: 5455252 (1995-10-01), Wilhelm et al.
patent: WO 01/46151 (2001-06-01), None
Deschenes Denis
Dube Daniel
Gallant Michel
Girard Yves
Lacombe Patrick
Merck Frosst Canada & Co.
Panzer Curtis C.
Rose David L.
Seaman D. Margaret
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