Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-11-30
1993-08-10
Lee, Mary C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5483127, 548111, 548112, 548119, 5483345, 5483371, 5483124, 5483335, 5483381, 548251, 548253, 5483147, 548187, 548194, 548204, 548225, 5483151, 5482644, 5482654, 5482666, 548225, 5483157, 548233, 548236, 548243, 548245, 5483154, 548247, 5483215, 5483241, 5483231, 5483315, 5483281, 5483285, 5483321, 5483331, 546 22, 546 24, 546278, 514398, 514399, 514400, 514381, 514382, 514369, 514370, 514365, 514341, 514383, 514384, 514359, 514374, 514376, 514377, 514378, 514380, 514 90, 514 93, 514 94, 514 89, A61K 31675,
Patent
active
052349179
ABSTRACT:
Angiotensin II receptor antagonists having the formula: ##STR1## which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.
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patent: 4355040 (1982-10-01), Furukawa et al.
Bolis et al.; J. Med. Chem.; 30; pp. 1729-1737; (1987).
Haber et al.; J. Cardiovas. Pharmacol. (1987) pp. 554-558.
Plattner et al.; J. Med. Chem.; 31; pp. 2277-2288, (1988).
Burger; Medicinal Chemistry 2nd Ed.; (1960) pp. 565-571, 579-601.
Denkewalter et al.; Progress in Drug Research; vol. 10; pp. 510-512 (1966).
Finkelstein Joseph A.
Hempel Judith
Keenan Richard M.
Samanen James
Weinstock Joseph
Lee Mary C.
Lentz Edward T.
McCarthy Mary E.
Venetianer Stephen
Whittenbaugh Robert C.
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