Substituted 4-pyrimidone compounds, compositions and methods of

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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424256, 544309, 544321, 546270, 546276, A61K 31505, C07D40312

Patent

active

042184525

ABSTRACT:
The compounds are substituted isocytosines which are histamine H.sub.2 -antagonists. Two specific compounds of the present invention are 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(3-methoxybenzyl)-4-py rimidone and 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-benzyloxy-4-pyrimidone .

REFERENCES:
patent: 3932644 (1976-01-01), Durant
Burger, Alfred, "Medicinal Chemistry", 2nd edition, Interscience Publishers, Nov. 4, 1960, pp. 42-43.

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