Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1975-11-20
1977-04-19
Helfin, Bernard
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2603455, 424283, C07D31102
Patent
active
040187985
ABSTRACT:
The present invention relates to substituted [4-oxo-4H-1-benzopyran-2-yl]cyclopropane carboxylic acids and esters having the following structural formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are hydrogen, alkyl, lower alkoxy, phenyl or when R.sub.1 and R.sub.2 are hydrogen, R.sub.3 and R.sub.4 taken together form an additional aromatic ring and A is hydrogen or ethyl. The compounds of this invention exhibit anti-allergy properties and are indicated in the management of allergic manifestations such as bronchial asthma.
REFERENCES:
patent: 3823165 (1974-07-01), Cairns et al.
patent: 3853921 (1974-12-01), Klutchko et al.
patent: 3948955 (1976-04-01), Lee et al.
Cohen Marvin P.
Shavel, Jr. John
VON Strandtmann Max
Chan Nicky
Chow Frank S.
Graddis Albert H.
Helfin Bernard
Warner-Lambert & Company
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