Substituted 4'-hydroxyphenyl guanidines and methods of using the

Details Substituted 4'-hydroxyphenyl guanidines and methods of using the Substituted 4'-hydroxyphenyl guanidines and methods of using the

1974-10-29

1977-03-29

Schwartz, Gerald A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26050114, 424316, 424326, C07C12908

Patent

active

040149340

ABSTRACT:
Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.

REFERENCES:
chem. Abstr. vol. 47 col. 3923(b).
Chem Abstr. vol. 29 col. 1504.sup.8 (1935).

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