Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1996-02-16
1998-10-13
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514316, 514318, 514343, 514352, 514353, 540597, 546187, 546208, 5462764, 5462791, 546292, 546297, A61K 3144, A61K 3155, C07D21374, C07D40112
Patent
active
058212396
ABSTRACT:
There are disclosed various substituted 4-amino-3-pyridinol compounds of the formula below, ##STR1## where R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification, which are useful for alleviating various memory dysfunctions characterized by a cholinergic deficit such as Alzheimer's disease.
REFERENCES:
patent: 4735958 (1988-04-01), Roth et al.
patent: 4859663 (1989-08-01), Greve et al.
Bellamy et al., Chemical Abstracts, vol. 90, abstract 203170, 1979.
Berger et al., Chemical Abstracts, vol. 111, abstract 108504, 1989.
Neurology by S H Appel, pp. 289-324 (1987).
Hrib Nicholas Joseph
Jurcak John Gerard
Kapples Kevin James
Shutske Gregory Micahel
Tomer John Dick
Frommer Lawrence & Huag LLP
Raymond Richard L.
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