Substituted 4-(amidino)benzamides of 1-azabicyclo[2.2.2]octan-3-

Details Substituted 4-(amidino)benzamides of 1-azabicyclo[2.2.2]octan-3- Substituted 4-(amidino)benzamides of 1-azabicyclo[2.2.2]octan-3-

1990-12-12

1991-12-03

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546133, A61K 31435, C07D22102

Patent

active

050700952

ABSTRACT:
Novel 1-(azabicyclo[2.2.2]oct-3- or -4-yl)benzamides substituted on the benzene ring with the basic substituted aminomethyleneamino group have been found to be useful in treating emesis, including emesis due to chemical and radiation anticancer therapy, anxiety, and impaired gastric emptying. These compounds are represented by Formula I below. ##STR1##

REFERENCES:
patent: 4593034 (1986-06-01), Munson et al.
patent: 4657911 (1987-04-01), Imbert et al.
Chem. Abs. 100, 174466e (Abstract of Spanish Patent ES 516729A1).
J. Med. Chem. 31, 1548-1558 (1988), Monkovic et al.

Affiliated with

Also associated with

Rating

Substituted 4-(amidino)benzamides of 1-azabicyclo[2.2.2]octan-3- does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted 4-(amidino)benzamides of 1-azabicyclo[2.2.2]octan-3-, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 4-(amidino)benzamides of 1-azabicyclo[2.2.2]octan-3- will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1697189