Substituted 4,5,6,7-tetrahydrobenzthiazol-2-ylamine compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S254040, C514S252130, C514S218000, C514S422000, C544S367000, C544S135000, C544S368000, C540S553000, C548S163000, C548S180000, C548S161000, C548S518000

Reexamination Certificate

active

07348347

ABSTRACT:
Substituted 4,5,6,7-tetrahydrobenzothiazol-2-ylamine compounds, a method for their production; pharmaceutical compositions comprising them, and methods of use for modulating biological functions and/or treating or inhibiting various medical conditions such as, e.g., depression and pain.

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Gray, E.G., et al., “The Isolation of Nerve Endings from Brain: An Electron-Microscopic Study of Cell Fragments Derived by Homogenization and Centrifugation”, Journal Anatomy, 1962, pp. 79-88, vol. 96, Cambridge.
Frink, M.C., et al., “Influence of Tramadol on Neurotransmitter Systems of the Rat Brain”, Arzneim.-Forsch./Drug Res., 1996, pp. 1029-1036, vol. 46 (II), 11, Germany.
Lowry, O.H., “Protein Measurement with the Folin Phenol Reagent”, The Journal of Bioogical Chemistry, 1951, pp. 265-275, Missouri.
International Preliminary Report on Patentability dated Oct. 4, 2006, including English translation and PCT/ISA/237 (Written Opinion of the International Searching Authority) (four (4) pages).

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