Substituted...

Details Substituted... Substituted...

2008-12-18

2011-11-15

McIntosh, III, Traviss C (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S042000, C514S043000, C514S045000, C536S027600

Reexamination Certificate

active

08058259

ABSTRACT:
The present invention provides substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters and pharmaceutical compositions containing the same that are selective agonists of A2Aadenosine receptors (ARs). These compounds and compositions are useful as pharmaceutical agents.

REFERENCES:
patent: 3892777 (1975-07-01), Gruenman et al.
patent: 4012495 (1977-03-01), Schmiechen et al.
patent: 4193926 (1980-03-01), Schmiechen et al.
patent: 4242345 (1980-12-01), Brenner et al.
patent: 4448721 (1984-05-01), DeLuca et al.
patent: 4559157 (1985-12-01), Smith et al.
patent: 4608392 (1986-08-01), Jacquet et al.
patent: 4665074 (1987-05-01), Amschler
patent: 4695660 (1987-09-01), Otte et al.
patent: 4820508 (1989-04-01), Wortzman
patent: 4824660 (1989-04-01), Angello et al.
patent: 4879296 (1989-11-01), Daluge et al.
patent: 4938949 (1990-07-01), Borch et al.
patent: 4956345 (1990-09-01), Miyasaka et al.
patent: 4965271 (1990-10-01), Mandell et al.
patent: 4968697 (1990-11-01), Hutchison
patent: 4992478 (1991-02-01), Geria
patent: 5070877 (1991-12-01), Mohiuddin et al.
patent: 5096906 (1992-03-01), Mandell et al.
patent: 5124455 (1992-06-01), Lombardo et al.
patent: 5140015 (1992-08-01), Olsson et al.
patent: 5189027 (1993-02-01), Miyashita et al.
patent: 5272153 (1993-12-01), Mandell et al.
patent: 5278150 (1994-01-01), Olsson et al.
patent: 5298508 (1994-03-01), Jacobson et al.
patent: 5364842 (1994-11-01), Spada et al.
patent: 5561111 (1996-10-01), Guerrant et al.
patent: 5561134 (1996-10-01), Spada et al.
patent: 5565462 (1996-10-01), Eitan et al.
patent: 5593973 (1997-01-01), Carter
patent: 5593975 (1997-01-01), Cristalli
patent: 5593976 (1997-01-01), Mongelli et al.
patent: 5665754 (1997-09-01), Feldman et al.
patent: 5668139 (1997-09-01), Belardinelli et al.
patent: 5696254 (1997-12-01), Mansour et al.
patent: 5731296 (1998-03-01), Sollevi
patent: 5756706 (1998-05-01), Mansour et al.
patent: 5776940 (1998-07-01), Daluge et al.
patent: 5854081 (1998-12-01), Linden et al.
patent: 5877180 (1999-03-01), Linden et al.
patent: 5877190 (1999-03-01), Dhainaut et al.
patent: 5932558 (1999-08-01), Cronstein et al.
patent: 5998386 (1999-12-01), Feldman
patent: 6004945 (1999-12-01), Fukunaga
patent: RE36494 (2000-01-01), Olsson et al.
patent: 6020321 (2000-02-01), Cronstein et al.
patent: 6020339 (2000-02-01), Perrier et al.
patent: 6034089 (2000-03-01), Han et al.
patent: 6060481 (2000-05-01), LaNoue et al.
patent: 6117878 (2000-09-01), Linden et al.
patent: 6232297 (2001-05-01), Linden et al.
patent: 6303619 (2001-10-01), Linden et al.
patent: 6322771 (2001-11-01), Linden et al.
patent: 6326359 (2001-12-01), Monaghan et al.
patent: 6332771 (2001-12-01), Adams et al.
patent: 6339072 (2002-01-01), Martin et al.
patent: 6350735 (2002-02-01), Monaghan
patent: 6387889 (2002-05-01), Endo et al.
patent: 6407076 (2002-06-01), Box et al.
patent: 6448235 (2002-09-01), Linden et al.
patent: 6455510 (2002-09-01), Charles et al.
patent: 6514949 (2003-02-01), Linden et al.
patent: 6525032 (2003-02-01), Mantrell et al.
patent: 6531457 (2003-03-01), Linden et al.
patent: 6545002 (2003-04-01), Linden et al.
patent: 6624158 (2003-09-01), Mantell et al.
patent: 6670334 (2003-12-01), Linden
patent: 6936596 (2005-08-01), Konno et al.
patent: 7214665 (2007-05-01), Linden et al.
patent: 7226913 (2007-06-01), Linden et al.
patent: 7307079 (2007-12-01), Den Hartog et al.
patent: 7378400 (2008-05-01), Rieger et al.
patent: 7396825 (2008-07-01), Okusa et al.
patent: 7427606 (2008-09-01), Linden et al.
patent: 7442687 (2008-10-01), Rieger et al.
patent: 7553823 (2009-06-01), Zablocki et al.
patent: 7576069 (2009-08-01), Rieger et al.
patent: 7589076 (2009-09-01), Rieger et al.
patent: 7605143 (2009-10-01), Rieger et al.
patent: 7737127 (2010-06-01), Linden et al.
patent: 7875595 (2011-01-01), Rieger et al.
patent: 7888329 (2011-02-01), Rieger et al.
patent: 2001/0027185 (2001-10-01), Linden et al.
patent: 2002/0032168 (2002-03-01), Mantrell et al.
patent: 2002/0058641 (2002-05-01), Mantell et al.
patent: 2002/0072597 (2002-06-01), Mantell et al.
patent: 2003/0013675 (2003-01-01), Yeadon et al.
patent: 2003/0162742 (2003-08-01), Linden et al.
patent: 2003/0186925 (2003-10-01), Palmer et al.
patent: 2003/0186926 (2003-10-01), Linden et al.
patent: 2004/0229246 (2004-11-01), Fishman et al.
patent: 2005/0004221 (2005-01-01), Hildebrand et al.
patent: 2005/0020532 (2005-01-01), Elzein et al.
patent: 2005/0182018 (2005-08-01), Linden et al.
patent: 2005/0261236 (2005-11-01), Okusa et al.
patent: 2005/0282831 (2005-12-01), Beauglehole et al.
patent: 2006/0030889 (2006-02-01), Ben-Haim et al.
patent: 2006/0040888 (2006-02-01), Rieger et al.
patent: 2006/0040889 (2006-02-01), Rieger et al.
patent: 2006/0052298 (2006-03-01), Guerrant et al.
patent: 2006/0100169 (2006-05-01), Rieger et al.
patent: 2006/0128652 (2006-06-01), Jagtap et al.
patent: 2006/0217343 (2006-09-01), Rieger et al.
patent: 2007/0027073 (2007-02-01), Rubinstein et al.
patent: 2007/0032450 (2007-02-01), Rieger
patent: 2007/0232559 (2007-10-01), Linden et al.
patent: 2007/0265440 (2007-11-01), Linden et al.
patent: 2008/0009460 (2008-01-01), Linden et al.
patent: 2008/0027022 (2008-01-01), Linden et al.
patent: 2008/0064653 (2008-03-01), Li et al.
patent: 2008/0214581 (2008-09-01), Allen et al.
patent: 2008/0262001 (2008-10-01), Kranenburg et al.
patent: 2008/0312160 (2008-12-01), Guerrant et al.
patent: 2009/0012035 (2009-01-01), Jacobson et al.
patent: 2009/0081764 (2009-03-01), Pausch et al.
patent: 2009/0118309 (2009-05-01), Beauglehole et al.
patent: 2009/0123510 (2009-05-01), Cronstein et al.
patent: 2009/0162292 (2009-06-01), Thompson et al.
patent: 2009/0170803 (2009-07-01), Linden et al.
patent: 2009/0181920 (2009-07-01), Watkins et al.
patent: 2009/0253647 (2009-10-01), Rieger et al.
patent: 2009/0280059 (2009-11-01), Rieger et al.
patent: 2009/0298788 (2009-12-01), Rieger et al.
patent: 2009/0325967 (2009-12-01), Fairhurst et al.
patent: 2010/0152127 (2010-06-01), Linden et al.
patent: 2010/0166698 (2010-07-01), Rieger
patent: 0488331 (1992-06-01), None
patent: 0488336 (1992-06-01), None
patent: 0488336 (1995-05-01), None
patent: 0700908 (1996-03-01), None
patent: 1110554 (2001-06-01), None
patent: 1150991 (2001-11-01), None
patent: 1194440 (2002-04-01), None
patent: 1194440 (2005-02-01), None
patent: 174074 (1979-10-01), None
patent: 0200224 (2002-06-01), None
patent: 144188 (2008-12-01), None
patent: 6299330 (1987-05-01), None
patent: 06299335 (1987-05-01), None
patent: 03287537 (1991-12-01), None
patent: 59197 (1993-01-01), None
patent: 59198 (1993-01-01), None
patent: 05025195 (1993-02-01), None
patent: 05163294 (1993-06-01), None
patent: 07508718 (1995-09-01), None
patent: 11335302 (1999-12-01), None
patent: 20007695 (2000-01-01), None
patent: 2002536300 (2002-10-01), None
patent: 530976 (2005-07-01), None
patent: WO-9005526 (1990-05-01), None
patent: WO-9015812 (1990-12-01), None
patent: WO-9109864 (1991-07-01), None
patent: WO-9322328 (1993-11-01), None
patent: WO-9602553 (1996-02-01), None
patent: WO-9604280 (1996-02-01), None
patent: WO-9847509 (1998-10-01), None
patent: WO-9852611 (1998-11-01), None
patent: WO-9857651 (1998-12-01), None
patent: WO-9857661 (1998-12-01), None
patent: WO-9934804 (1999-07-01), None
patent: WO-9938877 (1999-08-01), None
patent: WO-9941267 (1999-08-01), None
patent: WO-9962518 (1999-12-01), None
patent: WO-9963938 (1999-12-01), None
patent: WO-9967263 (1999-12-01), None
patent: WO-9967264 (1999-12-01), None
patent: WO-9967265 (1999-12-01), None
patent: WO-9967266 (1999-12-01), None
patent: WO-0012098 (2000-03-01), None
patent: WO-0023457 (2000-04-01), None
patent: WO-0044763 (2000-08-01), None
patent: WO-0044763 (2000-08-01), None
patent: WO-0072799 (2000-12-01), None
patent: WO-0078774 (2000-12-01), None
patent: WO-0078774 (2000-12-01), None
patent: WO-0078777 (2000-12-01), None
patent: WO-0078779 (2000-12-01), None
patent: WO-0194368 (2001-12-01), None
patent: WO-0209701 (2002-02-01), None
patent: WO-0222630 (2002-03-01), None
patent: WO-0209646

Affiliated with

Also associated with

Rating

Substituted... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Substituted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4291091