Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1989-03-13
1991-09-24
Chan, Nicky
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514542, 558417, 560 34, A61K 31275, A61K 3124, C07C12152, C07C10178
Patent
active
050514466
ABSTRACT:
The present invention relates to new compounds of the formula I ##STR1## as well as their preparation, pharmaceutical preparations containing same, and method of treating acute myocardial infarction.
The compounds which possess beta-adrenoceptor blocking activity are very shortacting and are preferably intended for treatment of acute myocardial infarction by administration by means of injection.
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Yusef, S., et al. "Early Intravenous Atenolol Treatment in Suspected Acute Myocardial Infarction", The Lancet, Aug. 9, 1980, pp. 273-276.
Frishman, W. H., "Clinical Pharmacology of the New Beta-Adrenergic Blocking Drugs. Part 12. Beta-Adrenocopetor Blockade in Myocardial Infarction: The Continuing Controversy", American Heart Journal, Apr. 1980, pp. 528-536.
Andersen, M., et al., "Effect of Alprenolol on Mortality Among Patients with Definite or Suspected Acute Myocardial Infarction", the Lancet, Oct. 27, 1979, pp. 865-867.
Sobel, B., "Propranolol and Threatened Myocardial," The New England Journal of Medicine, Jan. 25, 1979, pp. 191-193.
Mueller, H. S., "Beta Adrenergic Blockade in Acute Myocardial Infarction," Hospital Formulary, Nov., 1978, pp. 860-864.
Peter, T., "Reduction of Enzyme Levels by Propranolol After Myocardial Infarction," Circulation, Jun. 1978, pp. 1091-1095.
Lee, R. J., "Beta-Adrenergic Blockade in Acute Myocardial Infarction," Life Sciences, 1978, pp. 2539-2542.
Carlsson Enar I.
Gustafsson Bill B.
Lungren Bo T.
Chan Nicky
E. I. Du Pont de Nemours & Co.
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