Substituted 3-oxo-6-thia-2-azabicyclo (2.2.0) hexanes

Details Substituted 3-oxo-6-thia-2-azabicyclo (2.2.0) hexanes Substituted 3-oxo-6-thia-2-azabicyclo (2.2.0) hexanes

1978-09-11

1979-10-30

Randolph, John D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424275, 2602452, C07D51308

Patent

active

041728378

ABSTRACT:
Disclosed is the antibiotic 5-methyl-2-(1-carboxyl-2-methyl-propen-1-yl)-3-oxo-6-thia-2-azabicyclo [2.2.0] hexane (I): ##STR1## Also disclosed are processes for preparing I and its pharmaceutically acceptable salts and esters; pharmaceutical compositions comprising such compounds; and methods of treatment comprising administering such compounds and compositions when an antibiotic effect is indicated.

REFERENCES:
patent: 4126692 (1978-11-01), Di Ninno
Di Ninno et al., J. Org. Chem., vol. 42, pp. 2960 to 2965, (Sep. 1977).

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