Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1986-12-03
1989-07-04
Bond, Robert T.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
564 93, C07C14378
Patent
active
048452840
ABSTRACT:
This application discloses new substituted 3-nitrobenzensulfonamides which are useful in enhancing the effect of therapeutic radiation. It also discloses pharmaceutical composition of such compounds, and a method of treatment of patients by administering an effective amount of a substituted 3-nitrobenzenesulfonamide to a patient in need of radiation therapy.
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Halliwell, B. et al., Free Radicals in Biology and Medicine Oxford 1985, pp. 238-241.
Wardman, P. "Radiation Chemistry in the Clinic:Hypoxic Cell Radiosensitizers for Radiotherapy" manuscript to be published.
Engelhardt Edward L.
Saari Walfred S.
Bond Robert T.
Caruso Charles M.
Covington Raymond
Merck & Co. , Inc.
Meredith Roy D.
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