Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-10-10
2006-10-10
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S233800, C514S256000, C514S274000, C544S111000, C544S300000, C544S333000, C546S114000
Reexamination Certificate
active
07119102
ABSTRACT:
Disclosed are compounds of formula (I):wherein the variables R1, R2, R3and Z are described herein, which are useful as inhibitors of the kinase activity of the IκB kinase (IKK) complex. The compounds are therefore useful in the treatment of IKK mediated diseases including autoimmune diseases inflammatory diseases and cancer. Also disclosed are pharmaceutical compositions comprising these compounds and processes for preparing these compounds.
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patent: 2004/0180922 (2004-09-01), Cywin et al.
patent: 2005/0038104 (2005-02-01), Chen et al.
patent: WO 03/037886 (2003-05-01), None
patent: WO 03/103661 (2003-12-01), None
Karin et al. Nature Reviews Drug Discovery, 2004, 3, 17-26.
Chen Zhidong
Cirillo Pier Francesco
DiSalvo Darren
Liu Wei-min
Marshall Daniel Richard
Boehringer Ingelheim Pharmaceuticals Inc.
Devlin Mary-Ellen M.
Dow David
Morris Michael
Nolan Jason M.
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