Substituted 3-amino-pyrrolidino-4-lactams

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Details

C514S248000, C514S256000, C514S266200, C514S335000, C514S415000, C514S424000, C514S426000, C544S209000, C544S237000, C544S283000, C544S326000, C546S208000, C548S469000, C548S518000

Reexamination Certificate

active

07485641

ABSTRACT:
The invention provides compounds of formula (1),and the pharmaceutically acceptable salt thereof, wherein R1, n and R2are as described herein; compositions thereof; and uses thereof.

REFERENCES:
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patent: 2006/0135512 (2006-06-01), Boehringer et al.
patent: 2006/0241146 (2006-10-01), Yasuda et al.
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patent: 2007/0037785 (2007-02-01), Ansorge et al.
patent: WO03080633 (2003-10-01), None
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patent: WO2006097175 (2006-09-01), None
patent: WO2006104356 (2006-10-01), None
patent: WO2007024993 (2007-03-01), None
Liang et al., 30thNational Medicinal Chemistry Symposium, Jun. 28, 2006, “Design of Novel DPP-4 Inhibitors Using Structural Biology and Molecular Modeling”, #126.

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