Substituted 3-(1-aminoethylidene)-5-cinnamoyl-2H-pyran-2,6(3H)-d

Details Substituted 3-(1-aminoethylidene)-5-cinnamoyl-2H-pyran-2,6(3H)-d Substituted 3-(1-aminoethylidene)-5-cinnamoyl-2H-pyran-2,6(3H)-d

1976-02-18

1977-04-12

Demers, Arthur P.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Lipid or oil

260240J, 260240K, 424279, C07D30910

Patent

active

040176339

ABSTRACT:
Substituted 3-(1-aminoethylidene)-5-cinnamoyl-2H-pyran-2,6(3H)-diones useful as inhibitors of certain antigen-antibody reactions, particularly in alleviating allergic manifestations such as asthma, are prepared by reaction of a 3-(1-aminoethylidene)-5-acetyl-2H-pyran-2,6(3H)-dione with an appropriately substituted benzaldehyde.

REFERENCES:
patent: 3558658 (1971-01-01), McIntyre
patent: 3644635 (1972-02-01), Tate et al.
patent: 3751434 (1973-08-01), Lefebure
Wiley et al. J. Org. Chem. 21 (1956) pp. 686-688.
Kiang et al. J. Chem. Soc. (c) 1971, pp. 2721-2726.

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