Substituted 2-thio-3, 5-dicyano-4-phenyl-6-aminopyridines...

Details Substituted 2-thio-3, 5-dicyano-4-phenyl-6-aminopyridines... Substituted 2-thio-3, 5-dicyano-4-phenyl-6-aminopyridines...

2006-05-16

2006-05-16

Morris, Patricia L. (Department: 1625)

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C546S269700

Reexamination Certificate

active

07045631

ABSTRACT:
Compounds of the formula (I)a process for preparing them, and their use as medicaments are described.

REFERENCES:
patent: 2386147 (2001-12-01), None
patent: 0125210 (2001-12-01), None
“Adenosine Uptake Inhibitors”, Noji et. al., European J. Pharmacology 495 (2004), pp. 1-16.
Ca 134:295744, “Substituted 2-thio-3,5--dicyano-4-aryl-6-aminopyridines and the use thereof adenosine receptor ligands”, Rosentreter et. al.
Poulsen, S.-A., and Quinn, R. J., “Adenosine Receptors: New Opportunities for Future Drugs” Bioorganic & Medicinal Chemistry, 6: 619-641 (1998).
Olah, M.E. et al., “Cloning expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis,” J. Biol. Chem. 267, 10764-10770, (1992).
Klotz, K.N. et al., “Comparative pharmacalogy of human adenosine receptor subtypes—characterization of stably transfected receptors in CHO Cells.” Naunyn Schmiedebergs Arch. Pharmacol. 35, 1-9, (1998).
Poulsen, S.A. et al., “Adeonosine Receptors: New Opportunities for Future Drugs”. Bioorganic and Medicinal Chem, 6, 619-641, (1998).

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