Substituted 2-thiazolyl tetrazolium salt indicators

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548193, 548194, 548198, C07D41704, G01N 3700

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active

053226801

ABSTRACT:
2-Thiazolyl tetrazolium salt compounds characterized by a reflectance spectrum exhibiting an extended plateau above about 600-650 nm. Such compounds are useful as chromogenic indicators for reducing substances such as NADH. The reflectance plateau confers improved accuracy to analytical assays, particularly for the determination of analytes of medical diagnostic significance, in which a colorimetric response on a reagent carrier matrix is measured by reflectance.

REFERENCES:
patent: 3957514 (1976-05-01), Adir
Die Pharmazie, vol. 34, No. 12, 1979, pp. 790-794; S. Johne et al: Compound 3, p. 792, Tables 2 and 3.
Chemical Abstracts, vol. 95, No. 19, Nov. 9, 1981, Abstract No. 95:169190j.
Patent Abstracts of Japan, vol. 9, No. 211 (C-300) (1934) Aug. 29, 1985.

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