Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-01-04
2011-01-04
Davis, Zinna N (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S277000, C514S340000, C514S345000, C544S333000, C546S255000, C546S256000, C546S261000
Reexamination Certificate
active
07863280
ABSTRACT:
This invention relates to compounds of formula (I),wherein R1 and R3 independently represent fluorine, methoxy, —OCF3, C2-C3-alkenyl or C1-C4-alkyl which is optionally substituted by chlorine, methoxy or one, two or three fluorine atoms; R2 represents hydrogen, fluorine, methoxy, —OCF3, C2-C3-alkenyl or C1-C4-alkyl which is optionally substituted by chlorine, methoxy or one, two or three fluorine atoms; X represents O, S, NH or N(C1-C3-alkyl); and Ar represents an unsubstituted or at least monosubstituted aryl or heteroaryl. Said compounds are inhibitors of poly(ADP-ribose) polymerase (PARP), and may be used for the treatment of a variety of disorders.
REFERENCES:
patent: 2005/0080096 (2005-04-01), Ishida et al.
patent: 0109628 (1984-05-01), None
patent: WO 93/07137 (1993-04-01), None
Guessregen Stefan
Hofmeister Armin
Peukert Stefan
Schreuder Herman
Schwahn Uwe
Davis Zinna N
Farquharson-Torres Serena
Sanofi-Aventis Deutschland GmbH
LandOfFree
Substituted 2-pyridone derivatives, method for their... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted 2-pyridone derivatives, method for their..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 2-pyridone derivatives, method for their... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2674819