Substituted 2-phenyl benzofurans as estrogenic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Reexamination Certificate

active

07022733

ABSTRACT:
This invention provides estrogen receptor modulators of formula I, having the structurewhereinR, R′, A, A′, X, Y, and Y are as defined in the specification, or a pharmaceutically acceptable salt thereof.

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patent: WO 02/16333 (2002-02-01), None
Cameron, et al., “Photogeneration of amines from alpha-keto carbamates: photochemical studies,” J. Am. Chem. Soc. (1996) 118:12925-12937.
Lee and Balasubramanian. “Studies on a dithiane-protected benzoin photolabile safety catch linker for solid-phase synthesis.” J. Org. Chem. (1999) 64:3454-3460.
Teo, et al., “Synthesis of 2-(p-chlorobenzyl)-3-aryl-6-methoxybenzofurans as selective ligands for antiestrogen-binding sites. Effects on cell proliferation and cholesterol synthesis,” J. Med. Chem. (1992) 35:1330-1339.

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