Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-10-31
2006-10-31
Davis, Zinna N. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S287000
Reexamination Certificate
active
07129255
ABSTRACT:
This application relates to compounds of the formulawherein the groups R1–R6are as defined in the specification and claims, and to a pharmaceutical composition containing the same, and to a method of using the same in treatment of cardiovascular disorders.
REFERENCES:
patent: 2914534 (1959-11-01), Middleton
patent: 0282904 (1988-09-01), None
patent: 0705820 (1996-04-01), None
patent: 9727177 (1997-07-01), None
patent: 9919302 (1999-04-01), None
patent: 0125210 (2001-04-01), None
patent: 0162233 (2001-08-01), None
Olah, M.E. et al., “Cloning expression, and characterization of the unique bovine A1 adenosine receptor. Studies on the ligand binding site by site-directed mutagenesis.” J. Biol. Chem. 267 pp. 10764-10770 (1992).
Klotz, K.N. et al., “Comparative pharmacalogy of human adenosine receptor subtypes—characterization of stably transfected receptors in CHO Cells,” Naunyn Schmiedebergs Arch. Pharmacol. 357 1-9 (1998).
Poulsen, S.A. et al., “Adeonosine Receptors: New Opportunities for Future D rugs”, Bioorganic and Medicinal Chemistry, 6 619-641 (1998).
Broadley, K.J., “Drugs modulating adenosine receptors as potential therapeutic agents for cardiovascular diseases.” Exp. Opin. Ther. Patents, 10 1669-1692 (2000).
Dembowsky Klaus
Diedrichs Nicole
Hübsch Walter
Krahn Thomas
Krämer Thomas
Bayer Aktiengesellschaft
Davis Zinna N.
LandOfFree
Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Substituted 2-carba-3,5-dicyano-4-aryl-6-aminopyridines and... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3664973