Substituted 2-anilinopryimidines useful as protein kinase inhibi

Details Substituted 2-anilinopryimidines useful as protein kinase inhibi Substituted 2-anilinopryimidines useful as protein kinase inhibi

1998-03-13

2000-04-11

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544321, 544122, 5142358, 514252, A61K 31505, C07D40310

Patent

active

060488662

ABSTRACT:
Compounds of formula (1) are described: ##STR1## and the salts, solvates, hydrates and N-oxides thereof, in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 have the meanings given in claim 1. The compounds are selective inhibitors of protein kinases, especially src-family protein kinases and are of use in the prophylaxis and treatment of immune diseases, hyperproliferative disorders and other diseases in which inappropriate protein kinase action is believed to have a role.

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