Substituted 2-amidotetralins as melatonin agonists and antagonis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

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514613, 514616, 514619, 514624, 514625, 514628, 514629, A61K 31165, A61K 3116

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active

051514460

ABSTRACT:
The present invention relates generally to compounds having melatonin receptor activities and in particular to substituted 2-amidotetralin derivatives; to pharmaceutical preparations comprising such compounds; and to methods for using these compounds as therapeutic and diagnostic reagents.

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Merz et al., American Chemical Society, 1979, 1475.
Taylor et al., Life Sciences, vol. 41, pp. 1961-1969, 1987.
Hacksell et al., American Chemical Society, 1979, pp. 1469-1475.
Ames et al., Journal of the Chemical Society, Apr. 1969, 2635-2641.

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