Substituted 2,4-diamino-5-benzylpyrimidines, their preparation a

Details Substituted 2,4-diamino-5-benzylpyrimidines, their preparation a Substituted 2,4-diamino-5-benzylpyrimidines, their preparation a

1987-02-06

1990-03-27

Ford, John M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544325, C07D23949, A61K 31505

Patent

active

049121120

ABSTRACT:
Novel substituted 2,4-diamino-5-benzyl pyrimidines are described. The novel substances have antimicrobial activity and are particularly suitable for inhibiting the growth of mycobacteria. Combined with inhibitors such as diaminodiphenylsulphones, ring-substituted 4-aminodiphenylsulphones or ring and/or nitrogen-substituted diaminodiphenylsulphones, they have a marked synergistic activity.

REFERENCES:
patent: 4115650 (1978-09-01), Manchand
patent: 4143227 (1979-03-01), Rosen
patent: 4515948 (1985-05-01), Kompis et al.

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