Substituted 2,3-dihydro-1h-isoindol-1-one derivatives and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C546S277100, C546S152000, C546S139000, C546S113000, C548S472000, C544S111000, C514S416000, C514S314000, C514S307000, C514S300000, C514S231500

Reexamination Certificate

active

10926238

ABSTRACT:
Selected compounds are effective for prophylaxis and treatment of diseases, such as angiogenesis mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

REFERENCES:
patent: 5032598 (1991-07-01), Baldwin et al.
patent: 5215872 (1993-06-01), Goto et al.
patent: 5231099 (1993-07-01), Cook
patent: 5324743 (1994-06-01), Dillard et al.
patent: 5552441 (1996-09-01), Dillard et al.
patent: 5716993 (1998-02-01), Ozaki et al.
patent: 5789406 (1998-08-01), Aloup et al.
patent: 5789434 (1998-08-01), Kluender et al.
patent: 5798368 (1998-08-01), Muller et al.
patent: 5834463 (1998-11-01), Ohkawa et al.
patent: 5932582 (1999-08-01), Young et al.
patent: 6020358 (2000-02-01), Muller et al.
patent: 6172072 (2001-01-01), Lubisch et al.
patent: 6191161 (2001-02-01), Kanai et al.
patent: 6482951 (2002-11-01), Guertin
patent: 6667316 (2003-12-01), Man et al.
patent: 2003/0045552 (2003-03-01), Robarge et al.
patent: 0 887 340 (1998-12-01), None
patent: 0887340 (1998-12-01), None
patent: WO 90/05722 (1990-05-01), None
patent: WO 98/42666 (1998-10-01), None
patent: WO 98/54170 (1998-12-01), None
patent: WO 99/06041 (1999-02-01), None
patent: WO 99/31098 (1999-06-01), None
patent: WO 99/47512 (1999-09-01), None
Epsztajn et al., Application of organolithium and related reagents in aromatic metalation. A concise regiospecific conversion of benzoic acids into 4-hydroxy-1-arylnaphthalenes, TETRAHEDRON 49(4):929-38 (1993).
Baik et al., Preparation of novel 3,4-dialkoxyphenylisoindolinones as tumor necrosis factor-alpha, CA 129:275840, Reg. No. 214070-02-07.
Baik et al., Preparation of novel 3,4-dialkoxyphenylisoindolinones as tumor necrosis factor-alpha, CA 129:275840, Reg. No. 214069-97-3.
Shibata et al., Phenylphthalimides with Tumor Necrosis Factor Alpha Production-Enhancing Activity, Chemical & Pharmaceutical Bulletin 44(1):156-62 (1996).
Breier et al., “The role of vascular endothelial growth factor in blood vessel formation”, Trends in Cell Biology, 6:454-456 (1996).
Connell et al., “Patent focus on cancer chemotherapeutics. II Angiogenesis agents: Apr. 2000-Sep. 2000”, Expert Opinion on Therapeutic Patents, 11(1):77-114 (2001).
Da Settimo et al., “Reinvestigation of reductive butylation of aminophthalimides: new compounds with local anesthetic activity”, European Journal of Medicinal Chemistry, 24:263-270 (1989).
Sladowska et al., “Investigations on the synthesis and pharmacological properties of 4-alkoxy-2-[2-hydroxy-3-(4-aryl-1-piperazinyl)propyl]-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones”, II Farmaco, 57:897-908 (2002).

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