Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2008-04-21
2009-12-01
Seaman, D. Margaret (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
active
07626027
ABSTRACT:
The present invention discloses and claims compounds of formula (I)wherein M is N, and K and L are each C with the remaining substituents further defined herein. These compounds are effective as inhibitors of human casein kinase Iε, and as such are useful in the treatment of central nervous system diseases and disorders including mood disorders and sleep disorders. Pharmaceutical compositions comprising compounds of formula (I) and methods for the preparation of compounds of formula (I) are also disclosed and claimed.
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Camacho, F., et. al., Casein Kinase I and Circadian Rhythms: Effects of Manipulation of CKI Epsilon Activity on Period, Soc. for Neuroscience, Nov. 8-12, 2003, New Orleans, LA; Program No. 284.3. 2003 Abstract Viewer/Itinerary Planner. Washington, DC.
Harnish, S., et. al., Molecular Circadian Rhythms in Rat-1 Fibroblasts II: Pharmacological Manipulation of Period and Phase. , Soc. for Neuroscience, Nov. 8-12, 2003, New Orleans, LA, Program No. 284.2. 2003 Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2003.
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Camacho Fernando
Chiang Yulin
Choi-Sledeski Yong Mi
Doerflinger Gilles
Dutruc-Rosset Gilles
Aventis Pharmaceuticals Inc
Chandrakumar Nizal S
Gupta Balaram
Seaman D. Margaret
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