Substituted 10-oxo-10H-pyridazino(6,1-b)quinazoline-2-carboxylic

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544233, 544234, A61K 31505, C07D48704

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active

042501776

ABSTRACT:
The invention relates to substituted 10-oxo-10H-pyridazino(6,1-b)quinazoline-2-carboxylic acids having the formula: ##STR1## wherein R.sub.1 is hydrogen, halogen; R.sub.2 is hydrogen, lower alkyl containing one to three carbon atoms, or wherein R.sub.1 and R.sub.2 taken together with the carbon atoms to which they are attached in a benzo ring, and the pharmaceutically acceptable salts thereof. These compounds are useful as anti-allergic agents.

REFERENCES:
Beyer et al., I, Chem. Abs. 60, 9276g (1934).
Yanai et al., I, Chem. Abs. 63, 5638c (1965).
Beyer et al., II, Chem. Abs. 56, 5955c (1961).
Arya et al., Ind. J. Chem. 14B, 879-882 (1976).
Ghelardoni et al., Ann. d: Chimira 64, 445-453 (1974).
Chem. Abs., 8th Coll. Index, p. 264445.
Yanai et al., II, Chem. Abs. 70, 4034y (1968).

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