Substituted 10,11-dihydro-5,10-imino-[5H] dibenzo (a,d)-cyclohep

Details Substituted 10,11-dihydro-5,10-imino-[5H] dibenzo (a,d)-cyclohep Substituted 10,11-dihydro-5,10-imino-[5H] dibenzo (a,d)-cyclohep

1975-04-14

1977-02-22

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260283P, 260283R, 260286Q, 260287B, 260288CF, 260289C, C07D47108

Patent

active

040092739

ABSTRACT:
Racemates and optically active isomers of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, lower alkyl optionally substituted with a member of the group consisting of hydroxy and halogen, lower alkenyl, lower alkynyl, --(CH.sub.2).sub.n -- COCH.sub.3 where n is 0 or 1, ##STR2## wherein X is selected from the group consisting of lower alkyl and optionally substituted phenyl, aralkyl or 7 to 8 carbon atoms, acyl of an organic carboxylic acid of 1 to 6 carbon atoms optionally substituted with ##STR3## where m is an integer from 0 to 6 and X.sub.1 is selected from the group consisting of hydrogen and lower alkyl, ##STR4## where p is an integer from 1 to 6 and X.sub.1 is as before and ##STR5## wherein X.sub.2 is lower alkyl and R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen, halogen, lower alkyl, lower alkoxy, trifluoromethyl and dilower alkylamino and the non-toxic, pharmaceutically acceptable acid addition and quaternary ammonium salts thereof which have a stimulating effect on the central nervous system while possessing at the same time anticonvulsant activity and their preparation.

REFERENCES:
patent: 3597433 (1971-08-01), Dobson
patent: 3717641 (1973-02-01), Kocsis
patent: 3892756 (1975-07-01), Nedelec et al.

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