Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazep

Details Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazep Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazep

1977-02-02

1978-09-05

Siegel, A.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603323P, 2603323H, 2603472, 2603475, 2603477, 424275, C07D33324, C07D33316, A01N 900

Patent

active

041119576

ABSTRACT:
A group of 7,8-dihydroxy-2,3,4,5-tetrahydro-1H-3-benzazepines with structures containing a thienyl or furyl ring at position 1 which have dopaminergic activity. Particular species of this group include 7,8-dihydroxy-1-(5'-methyl-2'-thienyl)-2,3,4,5-tetrahydro-1H-3-benzazepine and its dimethyl ether derivative, 7,8-dihydroxy-1-(2'-thienyl)-2,3,4,5-tetrahydro-1H-3-benzazepine and its dimethyl ether as well as 7,8-dihydroxy-1-(3'-thienyl)-2,3,4,5-tetrahydro-1H-3-benzazepine and its dimethyl ether.

REFERENCES:
patent: 3393192 (1968-07-01), Walter
patent: 3663532 (1972-05-01), Sulkowski
Hartough, "Thiophene and HS Derivatives," (1952) p. 29.

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