Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...
Patent
1989-04-04
1992-05-12
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Nitrogen containing other than solely as a nitrogen in an...
564270, 568632, 568633, 568441, 568734, 568737, 568808, 514811, 514842, 514883, 514908, 514700, 514717, 514721, 514732, 514843, A61K 3113, C07C25124
Patent
active
051128691
ABSTRACT:
This invention concerns compounds having the structure: ##STR1## wherein each of R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, R.sup.7, R.sup.2', R.sup.3', R.sup.4', and R.sup.5', is independently hydrogen (--H), or a hydroxyl (--OH), methoxy (--OMe), methyl (--Me), carboxaldehyde (--CHO) or phenylformazen (Ph--N.dbd.CH--) group.
This invention also provides a novel process of synthesizing the compounds of the subject invention, including intermediate compounds useful in the process.
The present invention also provides pharmaceutical compositions comprising a pharmaceutically effective amount of a compound according to the subject invention and a pharmaceutically acceptable carrier. Finally, the invention provides spermicidal methods and methods of killing or of retarding the proliferation of, cancer cells.
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Huang Jai-Tung
Su Tsann-Long
Watanabe Kyoichi A.
Raymond Richard L.
Russell Mark W.
Sloan-Kettering Institute for Cancer Research
White John P.
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