Substituted 1-benzylindanes and their use as inhibitors of phosp

Details Substituted 1-benzylindanes and their use as inhibitors of phosp Substituted 1-benzylindanes and their use as inhibitors of phosp

1992-06-09

1994-03-01

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Aldehyde doai

568439, A61K 3111, C07C 4752

Patent

active

052908178

ABSTRACT:
The invention relates to benzylindane phospholipase A.sub.2 inhibitors, pharmaceutical compositions containing them, and methods of treating phospholipase A.sub.2 -mediated conditions in mammals by administration of a therapeutically effective amount of such a benzylindane phospholipase A.sub.2 inhibitor including the representative example: ##STR1##

REFERENCES:
patent: 3399049 (1968-08-01), Evans et al.
patent: 3904691 (1975-09-01), Carnmalm et al.
Chemical Abstracts 111: 190105, 1989.
Chemical Abstracts 77: 151743, 1972.
Chemical Abstracts 71: 70392, 1968.
Chemical Abstracts 70: 3838, 1968.
Chemical Abstracts 68: 75556, 1968.

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